Scientists Identify Saliva Biomarkers That Reveal Acute Sleep Deprivation
Researchers have discovered signs of sleep loss in saliva. Acute sleep deprivation can be detected using just a single saliva sample, the researchers report. This method could help improve road safety and safety in high-risk professions in the future. Good sleep is essential for our physical and mental health. And yet, sleep problems are widespread. According to the latest Swiss Health Survey, around one-third of the population report suffering from sleep disorders. Women and
A research team from the University of Zurich demonstrated that a single saliva sample can detect acute sleep loss. Using high‑resolution mass spectrometry and machine‑learning, they identified ten molecular markers that change after one night without sleep. The study involved 20 healthy young men under three sleep conditions, including total deprivation. The biomarkers were present in about 10 % of all salivary compounds. The researchers plan to validate the test in larger field trials, aiming for a rapid on‑site fatigue detector. Such a tool could improve safety for drivers and shift workers.
It could lead to practical tests that prevent accidents caused by sleep‑related fatigue.
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